ARMC2

Across TCGA cell cohorts, ARMC2 mutation is significantly associated with the mutation status of many other genes, with 4,663 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMC2-associated genes across cancer lineages are BDP1, GOT1, and LRRFIP1. Each is linked with ARMC2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARMC2-to-partner and partner-to-ARMC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BDP1 grouped by ARMC2-low versus ARMC2-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC2→partner) and Y-score (partner→ARMC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	BDP1 →	+3.095	+3.558	.008	.008	1	3
BLOOD_Lymphoma	GOT1 →	+4.429	+5.247	.005	.005	1	3
BLOOD_Lymphoma	LRRFIP1 →	+4.014	+4.969	.008	.008	1	3
BLOOD_Leukemia	YME1L1 →	+5.285	+4.321	.005	.005	1	3
BLOOD_Lymphoma	FAM81B →	+5.014	+5.584	.003	.003	1	3
BLOOD_Lymphoma	ZFYVE1 →	+4.429	+5.247	.005	.005	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,663 associations by consensus.

BDP1 by ARMC2 expression — BREAST

Explore this box plot interactively →