ARL8B

Across TCGA patient cohorts, ARL8B mutation is significantly associated with the RNA expression of many other genes, with 2,663 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL8B-associated genes across cancer lineages are RN7SL83P, IGHV3OR16-8, and CCL5. Each is linked with ARL8B in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL8B-to-partner and partner-to-ARL8B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL83P grouped by ARL8B-low versus ARL8B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL8B→partner) and Y-score (partner→ARL8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL83P →	+0.486	+5.392	<.001	.002	3	2
UCEC	IGHV3OR16-8 →	+0.509	+4.545	.007	<.001	3	1
UCEC	CCL5 →	+0.968	+2.828	.002	<.001	3	1
UCEC	MRPL20-DT →	+0.464	+3.716	.002	<.001	3	1
UCEC	DCP1A →	+0.438	+3.502	.007	.002	3	1
UCEC	C2orf15 →	+0.433	+2.354	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,663 associations by consensus.

RN7SL83P by ARL8B expression — COAD

Explore this box plot interactively →