ARL8A

Across TCGA patient cohorts, ARL8A RNA expression is significantly associated with the protein abundance of many other proteins, with 13,051 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARL8A-associated proteins across cancer lineages are IPO9, OTUD7B, and VANGL2. Each is linked with ARL8A in more than 5 cancer types. Because this analysis shows association rather than direction, both ARL8A-to-partner and partner-to-ARL8A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARL8A versus IPO9 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL8A→partner) and Y-score (partner→ARL8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IPO9 →	+0.322	+0.450	<.001	<.001	3	6
BRCA	OTUD7B →	+0.252	+0.473	<.001	<.001	3	5
BRCA	VANGL2 →	+0.612	+0.492	.001	.002	3	5
CCRCC	RPL34 →	-0.377	-0.217	.002	.002	3	5
BRCA	SNAP47 →	+0.265	+0.400	.002	.004	3	5
HNSC	RPRD2 →	+0.325	+0.552	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,051 associations by consensus.

ARL8A vs IPO9 — BRCA

Explore this scatter interactively →