ARL8A

Across TCGA patient cohorts, ARL8A mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL8A-associated genes across cancer lineages are RN7SL447P, MIR6801, and MRPS17P5. Each is linked with ARL8A in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL8A-to-partner and partner-to-ARL8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL447P grouped by ARL8A-low versus ARL8A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL8A→partner) and Y-score (partner→ARL8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL447P →	+0.184	+2.833	.002	.006	3	2
UCEC	MIR6801 →	+0.575	+2.806	.001	.003	3	1
UCEC	MRPS17P5 →	+0.193	+4.049	<.001	.008	3	1
SKCM	OR6C64P →	+0.059	+4.594	<.001	.008	3	1
SKCM	NMBR-AS1 →	+0.141	+4.513	<.001	.009	3	1
SKCM	FAM138A →	+0.028	+6.219	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

RN7SL447P by ARL8A expression — UCEC

Explore this box plot interactively →