ARL8A

Across TCGA patient cohorts, ARL8A mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL8A-associated genes across cancer lineages are aDC and Macrophages. Each is linked with ARL8A in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL8A-to-partner and partner-to-ARL8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, aDC grouped by ARL8A-low versus ARL8A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL8A→partner) and Y-score (partner→ARL8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	aDC →	+0.138	+2.815	<.001	.036	3	1
UCEC	Macrophages →	+0.018	+2.399	.022	.011	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

aDC by ARL8A expression — UCEC

Explore this box plot interactively →