ARL8A

Across TCGA cell cohorts, ARL8A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,597 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ARL8A-associated GO terms across cancer lineages are Endosomal transport, Cytosolic transport, and Post-Golgi vesicle-mediated transport. Each is linked with ARL8A in more than 15 cancer types. Because this analysis shows association rather than direction, both ARL8A-to-partner and partner-to-ARL8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by ARL8A-low versus ARL8A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL8A→partner) and Y-score (partner→ARL8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Endosomal transport →	+0.056	+0.692	<.001	.002	3	16
LARGE_INTESTINE	Cytosolic transport →	+0.065	+0.863	<.001	<.001	3	15
BREAST	Post-Golgi vesicle-mediated transport →	+0.071	+0.839	<.001	<.001	3	14
PANCREAS	Positive regulation of autophagy →	+0.057	+0.796	.002	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.062	+0.803	.007	.002	3	14
OESOPHAGUS	Regulation of endoplasmic reticulum unfolded protein response →	+0.120	+1.058	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,597 associations by consensus.

Endosomal transport by ARL8A expression — OESOPHAGUS

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