ARL6IP4

Across TCGA patient cohorts, ARL6IP4 mutation is significantly associated with the RNA expression of many other genes, with 149 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL6IP4-associated genes across cancer lineages are RNU1-139P, DHRS2, and DHDDS. Each is linked with ARL6IP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL6IP4-to-partner and partner-to-ARL6IP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-139P grouped by ARL6IP4-low versus ARL6IP4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL6IP4→partner) and Y-score (partner→ARL6IP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-139P →	+0.118	+4.414	.002	.004	3	2
UCEC	DHRS2 →	+1.111	+3.241	.003	.009	3	1
UCEC	DHDDS →	+0.437	+3.362	.004	.005	3	1
UCEC	VPS4A →	+0.543	+3.375	<.001	.004	3	1
UCEC	C9orf40 →	+0.782	+3.459	.002	.005	3	1
UCEC	MSTN →	+0.626	+3.234	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 149 associations by consensus.

RNU1-139P by ARL6IP4 expression — UCEC

Explore this box plot interactively →