ARL5C

Across TCGA pan-cancer cohorts, ARL5C Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ARL5C data layer compared with 23 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ARL5C Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ARL5C expression acts as an unfavorable survival marker.

COAD, LIHC, and UCEC are the cancer types where ARL5C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	II,III,IV	0.111	0.853	<.001	21	view →
LIHC	OS	Median	All	0.015	0.784	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ARL5C–COAD (OS)

Open the COAD breakdown →