ARL5C

Across TCGA cell cohorts, ARL5C RNA expression is significantly associated with the go_rna of many other GO terms, with 1,151 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARL5C-associated GO terms across cancer lineages are DNA topological change, Regulation of DNA repair, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with ARL5C in more than 7 cancer types. Because this analysis shows association rather than direction, both ARL5C-to-partner and partner-to-ARL5C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA topological change grouped by ARL5C-low versus ARL5C-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL5C→partner) and Y-score (partner→ARL5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	DNA topological change →	+0.094	+0.031	<.001	.006	3	8
STOMACH	Regulation of DNA repair →	+0.050	+0.031	<.001	.006	3	8
SOFT_TISSUE	Microtubule cytoskeleton organization involved in mitosis →	+0.073	+0.064	.001	.004	3	7
STOMACH	Positive regulation of DNA metabolic process →	+0.046	+0.033	.001	.003	3	6
BLOOD_Leukemia	DNA replication →	+0.077	+0.445	<.001	<.001	3	6
BONE	5S class rRNA transcription by RNA polymerase III →	+0.087	+0.068	.006	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,151 associations by consensus.

DNA topological change by ARL5C expression — STOMACH

Explore this box plot interactively →