ARL5AP5

Across TCGA pan-cancer cohorts, ARL5AP5 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ARL5AP5 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher ARL5AP5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ARL5AP5 expression acts as an unfavorable survival marker, although some lineages such as LUSC and LUAD show a favorable association.

MESO, LIHC, and BLCA are the cancer types where ARL5AP5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.036	0.563	<.001	54	view →
LIHC	OS	Tertile	All	0.511	0.708	.009	54	view →
BLCA	DFS	Tertile	III,IV	0.400	0.597	.007	42	view →
LUSC	OS	Quartile	All	0.860	0.731	.005	40	view →
KICH	OS	Tertile	II,III,IV	0.834	1.000	.002	39	view →
READ	OS	Quartile	II,III,IV	0.774	0.983	.002	39	view →
LGG	DFS	Tertile	All	0.272	0.436	<.001	33	view →
LUAD	OS	Tertile	II,III,IV	0.628	0.368	.015	27	view →
KIRC	DFS	Tertile	IV	0.293	0.530	.016	24	view →
OV	OS	Median	IV	0.762	0.493	.012	24	view →
SARC	OS	Tertile	All	0.914	0.674	.004	18	view →
TGCT	DFS	Median	All	0.938	0.727	.002	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ARL5AP5–MESO (OS)

Open the MESO breakdown →