ARL5AP5

Across TCGA pan-cancer cohorts, ARL5AP5 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ARL5AP5’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ARL5AP5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ARL5AP5 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

COAD, THCA, and UCEC are the cancer types where ARL5AP5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARL5AP5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.305	.008	5	view →
THCA	Male	All	−0.125	.020	4	view →
UCEC	All	III,IV	+0.196	.037	2	view →
STAD	All	IV	+0.156	.041	1	view →
LUSC	Female	II,III,IV	−0.131	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

ARL5AP5–COAD

Open the COAD breakdown →