ARL5A

Across TCGA patient cohorts, ARL5A protein abundance is significantly associated with the RNA expression of many other genes, with 4,164 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARL5A-associated genes across cancer lineages are BRCA1, TRIP13, and CDKN3. Each is linked with ARL5A in more than 3 cancer types. Because this analysis shows association rather than direction, both ARL5A-to-partner and partner-to-ARL5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARL5A versus BRCA1 in LUAD, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL5A→partner) and Y-score (partner→ARL5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BRCA1 →	-0.788	-0.301	.001	.008	3	4
LUAD	TRIP13 →	-1.106	-0.467	.007	.001	3	4
LUAD	CDKN3 →	-1.137	-0.395	<.001	<.001	3	3
LSCC	TMEM97 →	-1.060	-0.385	<.001	<.001	3	3
LUAD	NCAPH →	-0.910	-0.423	<.001	.001	3	3
LUAD	DLGAP5 →	-1.314	-0.384	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,164 associations by consensus.

ARL5A vs BRCA1 — LUAD

Explore this scatter interactively →