ARL5A

Across TCGA cell cohorts, ARL5A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,955 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARL5A-associated GO terms across cancer lineages are Subtelomeric heterochromatin formation, Transcription initiation at RNA polymerase I promoter, and Late viral transcription. Each is linked with ARL5A in more than 13 cancer types. Because this analysis shows association rather than direction, both ARL5A-to-partner and partner-to-ARL5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Subtelomeric heterochromatin formation grouped by ARL5A-low versus ARL5A-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL5A→partner) and Y-score (partner→ARL5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Subtelomeric heterochromatin formation →	+0.115	+0.627	<.001	<.001	3	14
SOFT_TISSUE	Transcription initiation at RNA polymerase I promoter →	+0.128	+0.945	<.001	<.001	3	13
LIVER	Late viral transcription →	+0.122	+0.608	<.001	.002	3	13
SOFT_TISSUE	Nuclear pore organization →	+0.150	+0.774	<.001	<.001	3	12
LIVER	Protein localization to Golgi membrane →	+0.152	+0.497	<.001	.003	3	12
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.087	+0.780	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,955 associations by consensus.

Subtelomeric heterochromatin formation by ARL5A expression — LARGE_INTESTINE

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