ARL5A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ARL5A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARL5A-associated genes across cancer lineages are CCL18. Each is linked with ARL5A in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL5A-to-partner and partner-to-ARL5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL18 grouped by ARL5A-low versus ARL5A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL5A→partner) and Y-score (partner→ARL5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECCL18 →+0.129+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CCL18 by ARL5A expression — LARGE_INTESTINE

Box plot of CCL18 in ARL5A-low vs ARL5A-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration