ARL4D

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARL4D mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL4D-associated genes across cancer lineages are NK cells and Melanocytes. Each is linked with ARL4D in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL4D-to-partner and partner-to-ARL4D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NK cells grouped by ARL4D-low versus ARL4D-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL4D→partner) and Y-score (partner→ARL4D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADNK cells →+0.011+5.597<.001.04031
UCECMelanocytes →+0.014+2.860.033.03411
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

NK cells by ARL4D expression — STAD

Box plot of NK cells in ARL4D-low vs ARL4D-high samples in STAD.

Explore this box plot interactively →

Exploration