ARL4C

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ARL4C mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARL4C-associated genes across cancer lineages are OR9A2, VN1R2, and OR14A16. Each is linked with ARL4C in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL4C-to-partner and partner-to-ARL4C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL4C→partner) and Y-score (partner→ARL4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaOR9A2 →+0.022+5.209<.001.00531
BLOOD_LymphomaVN1R2 →+0.006+5.643.003.00231
BLOOD_LymphomaOR14A16 →+0.023+5.643<.001.00231
BLOOD_LeukemiaNKX2-6 →+0.591+5.201<.001.00631
BLOOD_LeukemiaTLE7 →+0.042+5.969<.001.00131
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

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