ARL4AP1

Across TCGA pan-cancer cohorts, ARL4AP1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ARL4AP1 data layer compared with 14 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ARL4AP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ARL4AP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

COAD, CCRCC, and UCEC are the cancer types where ARL4AP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.877	1.000	.016	42	view →
CCRCC	OS	Tertile	All	0.696	0.950	.002	37	view →
UCEC	DFS	Tertile	II,III,IV	0.460	1.000	.009	28	view →
LSCC	DFS	Quartile	II,III,IV	0.482	0.933	.005	19	view →
GBM	OS	Quartile	All	0.343	0.709	<.001	12	view →
LUAD	DFS	Tertile	All	1.000	0.593	.017	3	view →
HNSC	OS	Tertile	III,IV	0.550	0.761	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ARL4AP1–COAD (DFS)

Open the COAD breakdown →