ARL4AP1

Across TCGA pan-cancer cohorts, ARL4AP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ARL4AP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ARL4AP1 RNA is repressed in tumor relative to normal tissue. In most cancer types ARL4AP1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH, BRCA, and STAD are the cancer types where ARL4AP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARL4AP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.034	.010	3	view →
BRCA	Female	All	+0.174	.044	2	view →
STAD	All	II,III,IV	+0.079	.007	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

ARL4AP1–KICH

Open the KICH breakdown →