ARL4A

Across TCGA patient cohorts, ARL4A protein abundance is significantly associated with the RNA expression of many other genes, with 14,261 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ARL4A-associated genes across cancer lineages are GRK3, TRIM9, and RASSF2. Each is linked with ARL4A in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL4A-to-partner and partner-to-ARL4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARL4A versus GRK3 in GBM, with a Pearson correlation of -0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL4A→partner) and Y-score (partner→ARL4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GRK3 →	-0.508	-0.770	<.001	<.001	3	1
GBM	TRIM9 →	+0.818	+0.779	.003	.001	3	1
GBM	RASSF2 →	+0.909	+0.732	.003	.007	3	1
GBM	KLF8 →	-0.622	-0.849	.002	.001	3	1
GBM	CYTH1 →	-0.659	-0.747	<.001	<.001	3	1
GBM	SLC9A3R1 →	-0.512	-0.877	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,261 associations by consensus.

ARL4A vs GRK3 — GBM

Explore this scatter interactively →