ARL4A

Across TCGA patient cohorts, ARL4A mutation is significantly associated with the RNA expression of many other genes, with 3,510 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL4A-associated genes across cancer lineages are PABPC1P5, KRTAP8-2P, and MIR4445. Each is linked with ARL4A in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL4A-to-partner and partner-to-ARL4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PABPC1P5 grouped by ARL4A-low versus ARL4A-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL4A→partner) and Y-score (partner→ARL4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	PABPC1P5 →	+0.644	+5.033	<.001	.009	3	2
LIHC	KRTAP8-2P →	+0.218	+6.008	<.001	.002	3	2
UCEC	MIR4445 →	+0.123	+3.893	<.001	.006	3	2
BLCA	LCN1P2 →	+0.198	+6.444	<.001	.001	3	2
UCEC	HNRNPA1P58 →	+0.124	+1.730	<.001	.002	3	2
UCEC	RNU6-1213P →	+0.130	+2.938	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,510 associations by consensus.

PABPC1P5 by ARL4A expression — LIHC

Explore this box plot interactively →