ARL4A

Across TCGA cell cohorts, ARL4A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,044 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARL4A-associated GO terms across cancer lineages are Transforming growth factor beta production, Transforming growth factor beta1 production, and Transport of virus. Each is linked with ARL4A in more than 8 cancer types. Because this analysis shows association rather than direction, both ARL4A-to-partner and partner-to-ARL4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transforming growth factor beta production grouped by ARL4A-low versus ARL4A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL4A→partner) and Y-score (partner→ARL4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transforming growth factor beta production →	+0.334	+1.321	<.001	.004	3	9
BONE	Transforming growth factor beta1 production →	+0.274	+1.114	.005	.003	3	7
BONE	Transport of virus →	+0.140	+1.339	.003	<.001	3	7
BONE	Intracellular transport of virus →	+0.140	+1.339	.003	<.001	3	7
BLOOD_Lymphoma	Positive regulation of translational initiation →	+0.082	+2.156	<.001	<.001	3	7
LIVER	Interleukin-10-mediated signaling pathway →	+0.204	+2.060	.003	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,044 associations by consensus.

Transforming growth factor beta production by ARL4A expression — BONE

Explore this box plot interactively →