ARL2BPP4

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, ARL2BPP4 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ARL2BPP4’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ARL2BPP4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ARL2BPP4 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUAD, BRCA, and LUSC are the cancer types where ARL2BPP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARL2BPP4 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUADFemaleAll+0.992<.0018view →
BRCAAllAll+0.267<.0016view →
LUSCAllAll−0.112.0015view →
COADAllAll+0.050.0341view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ARL2BPP4–LUAD

Tumor-vs-normal expression box plot for ARL2BPP4 RNA in LUAD.

Open the LUAD breakdown →

Exploration