ARL2BPP2

Across TCGA pan-cancer cohorts, ARL2BPP2 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated ARL2BPP2 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ARL2BPP2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ARL2BPP2 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, STAD, and ESCA are the cancer types where ARL2BPP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	IV	0.651	0.314	.010	93	view →
STAD	OS	Tertile	II,III,IV	0.461	0.689	.001	63	view →
ESCA	DFS	Tertile	All	0.250	0.517	<.001	45	view →
ACC	OS	Tertile	All	0.188	0.820	<.001	36	view →
LAML	DFS	Tertile	All	0.236	0.600	.008	30	view →
SKCM	DFS	Tertile	All	0.058	0.757	<.001	27	view →
KIRP	OS	Tertile	All	0.199	0.903	<.001	27	view →
LUAD	OS	Tertile	All	0.158	0.791	<.001	27	view →
GBM	DFS	Tertile	All	0.122	0.263	.028	9	view →
LIHC	OS	Tertile	All	0.105	0.774	.002	9	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

ARL2BPP2–HNSC (DFS)

Open the HNSC breakdown →