ARL2-SNX15

Across TCGA pan-cancer cohorts, ARL2-SNX15 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ARL2-SNX15 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ARL2-SNX15 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ARL2-SNX15 expression acts as an unfavorable survival marker, although some lineages such as COAD and UVM show a favorable association.

KIRC, COAD, and LUSC are the cancer types where ARL2-SNX15 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	All	0.433	0.664	<.001	79	view →
COAD	DFS	Tertile	All	0.845	0.642	.006	28	view →
LUSC	DFS	Median	II,III,IV	0.628	0.770	.007	28	view →
BRCA	OS	Quartile	All	0.945	0.967	.036	20	view →
UCEC	OS	Tertile	III,IV	0.722	0.839	.026	18	view →
CESC	DFS	Quartile	All	0.385	0.654	.004	16	view →
MESO	OS	Median	II,III,IV	0.305	0.686	.006	15	view →
HNSC	OS	Tertile	IV	0.296	0.627	.002	14	view →
KICH	OS	Quartile	All	0.846	0.980	.009	9	view →
UVM	OS	Median	II,III,IV	0.971	0.702	.009	9	view →
DLBC	DFS	Tertile	II,III,IV	0.416	0.878	.021	9	view →
PRAD	DFS	Tertile	All	0.929	0.865	.028	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ARL2-SNX15–KIRC (OS)

Open the KIRC breakdown →