ARL14EP

Across TCGA pan-cancer cohorts, ARL14EP mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ARL14EP data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ARL14EP mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ARL14EP expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where ARL14EP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	IV	0.785	0.123	.009	7	view →
LSCC	OS	Tertile	All	0.931	0.678	.015	6	view →
LUAD	OS	Median	II,III,IV	0.837	0.450	.026	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ARL14EP–CCRCC (OS)

Open the CCRCC breakdown →