ARL13B

Across TCGA patient cohorts, ARL13B mutation is significantly associated with the RNA expression of many other genes, with 4,250 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL13B-associated genes across cancer lineages are MIR548S, ZNF771, and CIDECP1. Each is linked with ARL13B in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL13B-to-partner and partner-to-ARL13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR548S grouped by ARL13B-low versus ARL13B-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL13B→partner) and Y-score (partner→ARL13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR548S →	+0.591	+5.043	<.001	<.001	3	2
UCEC	ZNF771 →	+0.455	+2.662	.001	<.001	3	2
UCEC	CIDECP1 →	+0.596	+2.716	<.001	<.001	3	2
UCEC	RPS19BP1 →	+0.502	+2.662	<.001	<.001	3	2
UCEC	RNU6-1082P →	+0.168	+2.381	<.001	.009	3	2
UCEC	RNA5SP223 →	+0.158	+2.919	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,250 associations by consensus.

MIR548S by ARL13B expression — LUAD

Explore this box plot interactively →