ARL13B

Across TCGA cell cohorts, ARL13B mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARL13B-associated genes across cancer lineages are LMX1A, CDR1, and GSTA2. Each is linked with ARL13B in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL13B-to-partner and partner-to-ARL13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LMX1A grouped by ARL13B-low versus ARL13B-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL13B→partner) and Y-score (partner→ARL13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	LMX1A →	+0.014	+3.906	<.001	.009	3	1
BLOOD_Myeloma	CDR1 →	+0.105	+3.906	.006	.009	3	1
BLOOD_Myeloma	GSTA2 →	+0.010	+3.906	.007	.009	3	1
BLOOD_Myeloma	MS4A12 →	+0.047	+3.906	<.001	.009	3	1
LUNG_NSCLC_LUAD	PRAMEF2 →	+0.008	+3.734	.001	.006	3	1
LUNG_NSCLC_LUAD	OR8B8 →	+0.019	+3.734	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

LMX1A by ARL13B expression — BLOOD_Myeloma

Explore this box plot interactively →