ARL11

Across TCGA patient cohorts, ARL11 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,095 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARL11-associated proteins across cancer lineages are PLEKHO2, RIN3, and SKAP2. Each is linked with ARL11 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARL11-to-partner and partner-to-ARL11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARL11 versus PLEKHO2 in GBM, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL11→partner) and Y-score (partner→ARL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLEKHO2 →	+0.447	+0.875	<.001	<.001	3	9
GBM	RIN3 →	+0.472	+0.798	<.001	<.001	3	8
GBM	SKAP2 →	+0.916	+0.945	<.001	<.001	3	8
GBM	APOBR →	+0.611	+0.784	<.001	<.001	3	8
GBM	WAS →	+0.789	+0.957	<.001	<.001	3	8
GBM	WDFY4 →	+0.551	+0.879	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,095 associations by consensus.

ARL11 vs PLEKHO2 — GBM

Explore this scatter interactively →