ARL11

Across TCGA patient cohorts, ARL11 mutation is significantly associated with the RNA expression of many other genes, with 3,692 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL11-associated genes across cancer lineages are RN7SL25P, RN7SL783P, and CDCA2. Each is linked with ARL11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL11-to-partner and partner-to-ARL11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL25P grouped by ARL11-low versus ARL11-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL11→partner) and Y-score (partner→ARL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RN7SL25P →	+0.192	+5.925	<.001	.002	3	2
READ	RN7SL783P →	+0.165	+5.653	<.001	.003	3	2
UCEC	CDCA2 →	+0.903	+2.874	<.001	<.001	3	2
COAD	BTBD6 →	+0.393	+4.053	.003	<.001	3	2
COAD	ZNF385C →	-0.337	-2.893	.009	.001	3	2
COAD	KIR2DL4 →	+0.421	+2.906	.006	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,692 associations by consensus.

RN7SL25P by ARL11 expression — READ

Explore this box plot interactively →