ARL11

Across TCGA cell cohorts, ARL11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,383 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARL11-associated GO terms across cancer lineages are Serotonin secretion, Cellular response to folic acid, and Serotonin production involved in inflammatory response. Each is linked with ARL11 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARL11-to-partner and partner-to-ARL11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Serotonin secretion grouped by ARL11-low versus ARL11-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL11→partner) and Y-score (partner→ARL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Serotonin secretion →	+1.489	+2.343	<.001	<.001	3	6
BLOOD_Lymphoma	Cellular response to folic acid →	+1.151	+1.932	<.001	<.001	3	6
BLOOD_Lymphoma	Serotonin production involved in inflammatory response →	+1.489	+2.343	<.001	<.001	3	6
BLOOD_Lymphoma	Serotonin secretion involved in inflammatory response →	+1.489	+2.343	<.001	<.001	3	6
BLOOD_Myeloma	Cytotoxic T cell degranulation →	+0.157	+0.634	.004	.004	3	6
BREAST	Regulation of synoviocyte proliferation →	-0.196	-0.538	.007	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,383 associations by consensus.

Serotonin secretion by ARL11 expression — BLOOD_Lymphoma

Explore this box plot interactively →