ARL10

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ARL10 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ARL10 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher ARL10 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ARL10 expression acts as an unfavorable survival marker.

SKCM are the cancer types where ARL10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMOSMedianAll0.1930.781<.0016view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

ARL10–SKCM (OS)

Kaplan–Meier survival curve for ARL10 mutant vs wild-type samples in SKCM.

Open the SKCM breakdown →

Exploration