ARID4A

Across TCGA patient cohorts, ARID4A RNA expression is significantly associated with the protein abundance of many other proteins, with 16,544 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ARID4A-associated proteins across cancer lineages are RPL7, PACS2, and UBR7. Each is linked with ARID4A in more than 5 cancer types. Because this analysis shows association rather than direction, both ARID4A-to-partner and partner-to-ARID4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARID4A versus RPL7 in GBM, with a Pearson correlation of -0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID4A→partner) and Y-score (partner→ARID4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL7 →	-0.479	-0.503	<.001	<.001	3	6
COAD	PACS2 →	+0.352	+0.495	.002	<.001	3	6
LSCC	UBR7 →	+0.432	+0.341	<.001	<.001	3	6
GBM	YLPM1 →	+0.255	+0.331	<.001	<.001	3	5
BRCA	ZFYVE1 →	+0.239	+0.486	<.001	.002	3	5
OV	PPIF →	-0.699	-0.534	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,544 associations by consensus.

ARID4A vs RPL7 — GBM

Explore this scatter interactively →