Across TCGA patient cohorts, ARID3C mutation is significantly associated with the RNA expression of many other genes, with 463 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARID3C-associated genes across cancer lineages are CYP4F27P, OR6B1, and RNU6-1245P. Each is linked with ARID3C in more than 1 cancer types. Because this analysis shows association rather than direction, both ARID3C-to-partner and partner-to-ARID3C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID3C→partner) and Y-score (partner→ARID3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CYP4F27P →	+0.169	+3.086	.003	.004	3	2
BRCA	OR6B1 →	+0.130	+5.610	<.001	.004	3	2
LUAD	RNU6-1245P →	+0.381	+4.116	<.001	.004	3	2
SKCM	RNU4ATAC17P →	+0.620	+2.693	.009	.006	3	2
LUAD	OR7K1P →	+0.023	+4.612	<.001	.006	3	2
UCEC	SNORA10B →	+0.221	+2.709	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 463 associations by consensus.

Exploration

ARID3C survival (RNA) · tumor vs normal (RNA) · all ARID3C data types