ARID3B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARID3B mutation is significantly associated with the RNA expression of many other genes, with 2,734 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARID3B-associated genes across cancer lineages are RN7SL474P, ATP1B2, and ARRDC3-AS1. Each is linked with ARID3B in more than 2 cancer types. Because this analysis shows association rather than direction, both ARID3B-to-partner and partner-to-ARID3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL474P grouped by ARID3B-low versus ARID3B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID3B→partner) and Y-score (partner→ARID3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARN7SL474P →+0.158+5.899<.001.00233
UCECATP1B2 →-0.624-3.076.002<.00133
UCECARRDC3-AS1 →+0.208+1.606.002.00332
HNSCMIR4799 →+0.535+6.008<.001.00232
HNSCRNU6-128P →+0.559+5.578<.001.00432
HNSCAFF2-IT1 →+0.113+5.822<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,734 associations by consensus.

RN7SL474P by ARID3B expression — BLCA

Box plot of RN7SL474P in ARID3B-low vs ARID3B-high samples in BLCA.

Explore this box plot interactively →

Exploration