ARID3B

Across TCGA patient cohorts, ARID3B mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARID3B-associated genes across cancer lineages are eEF2, EGFR_pY1068, and eIF4E. Each is linked with ARID3B in more than 1 cancer types. Because this analysis shows association rather than direction, both ARID3B-to-partner and partner-to-ARID3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by ARID3B-low versus ARID3B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID3B→partner) and Y-score (partner→ARID3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.268	+1.247	.028	.045	3	2
UCEC	EGFR_pY1068 →	-0.254	-1.807	.002	.004	3	2
UCEC	eIF4E →	+0.170	+2.472	.017	.010	3	2
UCEC	INPP4B →	-0.227	-1.807	.039	.024	3	2
COAD	TFRC →	+0.791	+2.841	.002	.033	3	2
UCEC	ERK2 →	+0.210	+2.222	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

eEF2 by ARID3B expression — UCEC

Explore this box plot interactively →