ARID3B

Across TCGA cell cohorts, ARID3B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,630 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARID3B-associated GO terms across cancer lineages are DNA replication proofreading, Transcription pausing by RNA polymerase II, and Regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with ARID3B in more than 10 cancer types. Because this analysis shows association rather than direction, both ARID3B-to-partner and partner-to-ARID3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication proofreading grouped by ARID3B-low versus ARID3B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID3B→partner) and Y-score (partner→ARID3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication proofreading →	+0.236	+1.125	.001	.004	3	11
LIVER	Transcription pausing by RNA polymerase II →	+0.144	+1.959	.002	.003	3	11
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.234	+1.444	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Long-chain fatty acid metabolic process →	-0.067	-0.824	<.001	.001	3	10
STOMACH	Negative regulation of mRNA metabolic process →	+0.094	+1.577	.001	.002	2	11
LARGE_INTESTINE	Regulation of translation at postsynapse, modulating synaptic transmission →	+0.085	+0.917	.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,630 associations by consensus.

DNA replication proofreading by ARID3B expression — BONE

Explore this box plot interactively →