ARHGEF38-IT1

Across TCGA patient cohorts, ARHGEF38-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,956 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ARHGEF38-IT1-associated proteins across cancer lineages are TMC5_S184, ARHGEF38_S55, and RAB19. Each is linked with ARHGEF38-IT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARHGEF38-IT1-to-partner and partner-to-ARHGEF38-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF38-IT1 versus TMC5_S184 in BRCA, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF38-IT1→partner) and Y-score (partner→ARHGEF38-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMC5_S184 →	+1.512	+0.667	<.001	<.001	3	6
HNSC	ARHGEF38_S55 →	+1.651	+0.989	<.001	<.001	3	6
LUAD	RAB19 →	+0.483	+1.182	<.001	<.001	3	6
UCEC	TMEM63A →	+0.510	+1.226	.003	.001	3	5
UCEC	TSPAN8 →	+2.042	+1.247	<.001	<.001	3	5
PDAC	OCLN →	+0.518	+1.018	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,956 associations by consensus.

ARHGEF38-IT1 vs TMC5_S184 — BRCA

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