ARHGEF38-IT1

Across TCGA pan-cancer cohorts, ARHGEF38-IT1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ARHGEF38-IT1 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher ARHGEF38-IT1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ARHGEF38-IT1 expression acts as an unfavorable survival marker, although some lineages such as OV and UCEC show a favorable association.

OV, THYM, and UCEC are the cancer types where ARHGEF38-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Tertile	II,III,IV	0.790	0.662	.007	84	view →
THYM	OS	Tertile	All	0.186	0.931	.001	63	view →
UCEC	DFS	Median	III,IV	0.676	0.447	.007	52	view →
BRCA	DFS	Quartile	All	0.963	0.926	.011	30	view →
ESCA	OS	Quartile	II,III,IV	0.330	1.000	.008	27	view →
UCS	OS	Tertile	II,III,IV	0.207	0.546	.031	18	view →
PAAD	DFS	Quartile	II,III,IV	0.521	0.333	.011	12	view →
LUAD	DFS	Median	IV	0.899	0.512	.006	10	view →
CHOL	OS	Median	IV	0.208	0.948	.010	9	view →
SARC	DFS	Tertile	All	0.051	0.596	<.001	9	view →
LIHC	OS	Tertile	III,IV	0.346	0.653	.004	6	view →
READ	OS	Median	All	0.529	0.943	.033	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ARHGEF38-IT1–OV (OS)

Open the OV breakdown →