Across TCGA patient cohorts, ARHGEF37 protein abundance is significantly associated with the protein abundance of many other proteins, with 25,143 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ARHGEF37-associated proteins across cancer lineages are BIN3, ARHGEF37_S251, and SLC4A1AP. Each is linked with ARHGEF37 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARHGEF37-to-partner and partner-to-ARHGEF37 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF37→partner) and Y-score (partner→ARHGEF37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BIN3 →	+0.613	+0.663	<.001	<.001	3	10
OV	ARHGEF37_S251 →	+1.180	+0.610	.001	.002	2	10
UCEC	SLC4A1AP →	-0.383	-0.478	<.001	<.001	3	8
GBM	USP39 →	-0.303	-0.380	<.001	<.001	3	8
GBM	RFC4 →	-0.390	-0.408	<.001	<.001	3	7
BRCA	RRP1B →	-0.363	-0.383	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,143 associations by consensus.

Exploration

ARHGEF37 survival (RNA) · tumor vs normal (RNA) · all ARHGEF37 data types