Across TCGA cell cohorts, ARHGEF35 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible ARHGEF35-associated genes across cancer lineages are SERPINA7, HBG1, and TAC1. Each is linked with ARHGEF35 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGEF35-to-partner and partner-to-ARHGEF35 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF35→partner) and Y-score (partner→ARHGEF35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	SERPINA7 →	+0.074	+4.491	<.001	.002	3	1
PANCREAS	HBG1 →	+0.059	+3.201	<.001	.008	3	1
PANCREAS	TAC1 →	+0.121	+3.724	.002	.004	3	1
LARGE_INTESTINE	OR5V1 →	+0.006	+4.022	<.001	.006	3	1
STOMACH	POTEB2 →	+0.006	+5.285	<.001	.003	3	1
STOMACH	POTEB →	+0.006	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

ARHGEF35 survival (RNA) · tumor vs normal (RNA) · all ARHGEF35 data types