Across TCGA patient cohorts, ARHGEF28 protein abundance is significantly associated with the RNA expression of many other genes, with 8,393 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGEF28-associated genes across cancer lineages are RNU7-196P, MRPS36, and STPG1. Each is linked with ARHGEF28 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGEF28-to-partner and partner-to-ARHGEF28 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF28→partner) and Y-score (partner→ARHGEF28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNU7-196P →	+1.211	+0.431	<.001	<.001	3	4
LUAD	MRPS36 →	+0.393	+0.400	<.001	<.001	3	4
LSCC	STPG1 →	+0.607	+0.412	<.001	<.001	3	4
BRCA	CXCL13 →	-1.731	-0.370	.006	.001	3	4
LSCC	COX7C →	+0.402	+0.339	<.001	.001	3	4
LUAD	F2RL1 →	+0.925	+0.374	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,393 associations by consensus.

Exploration

ARHGEF28 survival (RNA) · tumor vs normal (RNA) · all ARHGEF28 data types