Across TCGA cell cohorts, ARHGEF28 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,419 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARHGEF28-associated GO terms across cancer lineages are Regulation of cell junction assembly, Regulation of Rho protein signal transduction, and Regulation of actin filament polymerization. Each is linked with ARHGEF28 in more than 12 cancer types. Because this analysis shows association rather than direction, both ARHGEF28-to-partner and partner-to-ARHGEF28 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF28→partner) and Y-score (partner→ARHGEF28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell junction assembly →	+0.073	+1.810	.001	.003	3	13
OESOPHAGUS	Regulation of Rho protein signal transduction →	+0.127	+1.546	.005	.001	2	12
BREAST	Regulation of actin filament polymerization →	+0.064	+1.376	<.001	<.001	3	11
BONE	Positive regulation of plasma membrane repair →	+0.234	+1.814	<.001	<.001	3	11
BONE	Regulation of actin filament depolymerization →	+0.129	+1.621	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of macrophage fusion →	+0.261	+1.172	.009	.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,419 associations by consensus.

Exploration

ARHGEF28 survival (RNA) · tumor vs normal (RNA) · all ARHGEF28 data types