ARHGEF19

Across TCGA patient cohorts, ARHGEF19 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,501 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGEF19-associated proteins across cancer lineages are ARHGEF19_S197, RCC2, and THOC1. Each is linked with ARHGEF19 in more than 4 cancer types. Because this analysis shows association rather than direction, both ARHGEF19-to-partner and partner-to-ARHGEF19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF19 versus ARHGEF19_S197 in LSCC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF19→partner) and Y-score (partner→ARHGEF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGEF19_S197 →	+0.893	+0.756	<.001	<.001	3	5
BRCA	RCC2 →	+0.410	+1.014	<.001	<.001	3	5
HNSC	THOC1 →	+0.238	+0.953	<.001	.001	3	4
LSCC	THOC2 →	+0.301	+1.084	<.001	<.001	3	4
BRCA	TRIM2 →	+0.553	+0.810	.002	<.001	3	4
CCRCC	RCC1 →	+0.407	+0.610	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,501 associations by consensus.

ARHGEF19 vs ARHGEF19_S197 — LSCC

Explore this scatter interactively →