ARHGEF19

Across TCGA patient cohorts, ARHGEF19 mutation is significantly associated with the RNA expression of many other genes, with 1,758 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGEF19-associated genes across cancer lineages are RNA5SP167, LINC01763, and RN7SL184P. Each is linked with ARHGEF19 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARHGEF19-to-partner and partner-to-ARHGEF19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP167 grouped by ARHGEF19-low versus ARHGEF19-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF19→partner) and Y-score (partner→ARHGEF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP167 →	+0.367	+4.392	.005	.006	3	2
COAD	LINC01763 →	+0.194	+3.588	<.001	.007	3	2
COAD	RN7SL184P →	+0.244	+4.212	<.001	.002	3	2
PRAD	RNU6-918P →	+0.535	+5.166	<.001	.007	3	2
PRAD	TOMM22P3 →	+0.457	+5.490	<.001	.005	3	2
SKCM	RN7SL764P →	+0.050	+3.021	.006	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,758 associations by consensus.

RNA5SP167 by ARHGEF19 expression — COAD

Explore this box plot interactively →