ARHGEF10L

Across TCGA cell cohorts, ARHGEF10L RNA expression is significantly associated with the go_rna of many other GO terms, with 5,007 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ARHGEF10L-associated GO terms across cancer lineages are Cilium-dependent cell motility, Negative regulation of protein-containing complex assembly, and Cilium movement. Each is linked with ARHGEF10L in more than 12 cancer types. Because this analysis shows association rather than direction, both ARHGEF10L-to-partner and partner-to-ARHGEF10L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium-dependent cell motility grouped by ARHGEF10L-low versus ARHGEF10L-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF10L→partner) and Y-score (partner→ARHGEF10L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.121	-1.503	<.001	<.001	3	13
BONE	Negative regulation of protein-containing complex assembly →	+0.094	+1.436	.002	<.001	3	13
BONE	Cilium movement →	-0.099	-1.606	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.123	-1.350	<.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.121	-1.503	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.123	-1.350	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,007 associations by consensus.

Cilium-dependent cell motility by ARHGEF10L expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →