ARHGDIA

Across TCGA patient cohorts, ARHGDIA protein abundance is significantly associated with the RNA expression of many other genes, with 13,497 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGDIA-associated genes across cancer lineages are EXO1, MCM4, and KIF20A. Each is linked with ARHGDIA in more than 6 cancer types. Because this analysis shows association rather than direction, both ARHGDIA-to-partner and partner-to-ARHGDIA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGDIA versus EXO1 in BRCA, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGDIA→partner) and Y-score (partner→ARHGDIA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EXO1 →	-0.939	-0.260	<.001	<.001	3	7
LUAD	MCM4 →	-0.702	-0.158	.001	.008	3	6
CCRCC	KIF20A →	-0.856	-0.215	<.001	<.001	3	6
BRCA	CDC20 →	-1.200	-0.259	<.001	<.001	3	6
OV	GIMAP4 →	+0.758	+0.237	.002	.002	3	6
LUAD	CCNB1 →	-1.017	-0.163	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,497 associations by consensus.

ARHGDIA vs EXO1 — BRCA

Explore this scatter interactively →