ARHGDIA

Across TCGA cell cohorts, ARHGDIA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,592 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARHGDIA-associated GO terms across cancer lineages are Protein depolymerization, rRNA 5'-end processing, and CMP biosynthetic process. Each is linked with ARHGDIA in more than 10 cancer types. Because this analysis shows association rather than direction, both ARHGDIA-to-partner and partner-to-ARHGDIA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein depolymerization grouped by ARHGDIA-low versus ARHGDIA-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGDIA→partner) and Y-score (partner→ARHGDIA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Protein depolymerization →	+0.097	+0.593	.001	.005	3	11
UPPER_AERODIGESTIVE_TRACT	rRNA 5'-end processing →	+0.113	+0.783	.002	.001	3	11
LUNG_NSCLC_LUSC	CMP biosynthetic process →	+0.132	+0.824	.002	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.113	+0.783	.002	.001	3	11
OVARY	Positive regulation of mitotic cytokinesis →	+0.125	+0.879	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.236	+0.731	<.001	.009	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,592 associations by consensus.

Protein depolymerization by ARHGDIA expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →