ARHGAP8

Across TCGA patient cohorts, ARHGAP8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,551 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ARHGAP8-associated proteins across cancer lineages are CD163, CGAS, and FAM114A2. Each is linked with ARHGAP8 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGAP8-to-partner and partner-to-ARHGAP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP8 versus CD163 in PDAC, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP8→partner) and Y-score (partner→ARHGAP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CD163 →	-0.413	-0.539	.001	.001	3	4
BRCA	CGAS →	-0.493	-0.589	<.001	<.001	3	4
COAD	FAM114A2 →	-0.215	-0.661	.001	<.001	3	4
BRCA	NRBF2 →	-0.295	-0.661	.002	.003	3	4
HNSC	ZBED4_S624 →	+0.607	+0.974	<.001	<.001	3	4
HNSC	DCTN5 →	-0.252	-0.898	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,551 associations by consensus.

ARHGAP8 vs CD163 — PDAC

Explore this scatter interactively →