ARHGAP6

Across TCGA patient cohorts, ARHGAP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,313 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGAP6-associated proteins across cancer lineages are SYNPO2, TNXB, and KANK2. Each is linked with ARHGAP6 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARHGAP6-to-partner and partner-to-ARHGAP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP6 versus SYNPO2 in HNSC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP6→partner) and Y-score (partner→ARHGAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SYNPO2 →	+0.860	+0.429	<.001	<.001	3	9
BRCA	TNXB →	+0.762	+0.462	<.001	<.001	3	9
BRCA	KANK2 →	+0.719	+0.749	<.001	<.001	3	9
UCEC	PPP1R12C →	+0.404	+0.716	<.001	<.001	3	8
UCEC	SORBS3 →	+0.423	+0.647	<.001	<.001	3	8
BRCA	SSC5D →	+0.995	+0.687	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,313 associations by consensus.

ARHGAP6 vs SYNPO2 — HNSC

Explore this scatter interactively →