ARHGAP5-AS1

Across TCGA pan-cancer cohorts, ARHGAP5-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of ARHGAP5-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ARHGAP5-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ARHGAP5-AS1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, LUSC, and LIHC are the cancer types where ARHGAP5-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARHGAP5-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.503	<.001	11	view →
LUSC	Male	II,III,IV	+1.068	<.001	8	view →
LIHC	Male	All	+0.760	<.001	8	view →
KICH	All	All	−0.649	<.001	7	view →
BRCA	Female	II,III,IV	−1.184	<.001	6	view →
KIRP	All	II,III,IV	+0.660	.003	6	view →
THCA	All	IV	−0.647	.001	6	view →
CHOL	All	All	+1.350	<.001	5	view →
BLCA	Male	III,IV	−0.894	<.001	4	view →
UCEC	All	All	−0.563	.001	2	view →
LUAD	All	II,III,IV	+0.379	.023	2	view →
PRAD	All	All	−0.342	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

ARHGAP5-AS1–KIRC

Open the KIRC breakdown →